USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: Q9UBQ7 USC-OGP 2-DE database:  Q9UBQ7 Q9UBQ7 General information about the entry View entry in simple text format Entry name GRHPR_HUMAN Primary accession number Q9UBQ7 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Glyoxylate reductase/hydroxypyruvate reductase; EC=1.1.1.79; EC=1.1.1.81;. Gene name Name=GRHPR Synonyms=GLXR ORFNames=MSTP035 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1219: pI=6.47; Mw=36158 Cross-references UniProtKB/Swiss-Prot Q9UBQ7; GRHPR_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name GRHPR_HUMAN Primary accession number Q9UBQ7 Secondary accession number(s) Q5T945 Q9H3E9 Q9H636 Q9UKX1 Sequence was last modified on  May 1, 2000 (version 1) Annotations were last modified on  March 15, 2017 (version 157) Name and origin of the protein Description RecName: Full=Glyoxylate reductase/hydroxypyruvate reductase; EC=1.1.1.79; EC=1.1.1.81; Gene name Name=GRHPR Synonyms=GLXR ORFNames=MSTP035 Encoded on Name=GRHPR; Synonyms=GLXR; ORFNames=MSTP035 Keywords 3D-structure; Alternative splicing; Complete proteome; NADP; Oxidoreductase; Phosphoprotein; Polymorphism; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF134895; AAF00111.1; -; mRNA EMBL AF146018; AAD45886.1; -; mRNA EMBL AF146689; AAD46517.1; -; Genomic_DNA EMBL AF113215; AAG39286.1; ALT_FRAME; mRNA EMBL AK026287; BAB15430.1; -; mRNA EMBL AK315690; BAG38053.1; -; mRNA EMBL AL158155; CAI13848.1; -; Genomic_DNA EMBL CH471071; EAW58284.1; -; Genomic_DNA EMBL CH471071; EAW58285.1; -; Genomic_DNA EMBL BC000605; AAH00605.1; -; mRNA EMBL AF113251; AAD54066.1; ALT_FRAME; mRNA CCDS CCDS6609.1; -. [Q9UBQ7-1]; . PIR JC7190; JC7190; . RefSeq NP_036335.1; NM_012203.1. [Q9UBQ7-1]; . UniGene Hs.155742; -; . PDB 2GCG; X-ray; 2.20 A; A/B/C/D=1-328 PDB 2H1S; X-ray; 2.45 A; A/B/C/D=2-328 PDB 2Q50; X-ray; 2.45 A; A/B/C/D=2-328 PDB 2WWR; X-ray; 2.82 A; A/B/C/D=1-328 PDBsum 2GCG; -; . PDBsum 2H1S; -; . PDBsum 2Q50; -; . PDBsum 2WWR; -; . ProteinModelPortal Q9UBQ7; -; . SMR Q9UBQ7; -; . BioGrid 114781; 32; . IntAct Q9UBQ7; 5; . MINT MINT-5005010; -; . STRING 9606.ENSP00000313432; -; . iPTMnet Q9UBQ7; -; . PhosphoSitePlus Q9UBQ7; -; . SwissPalm Q9UBQ7; -; . BioMuta GRHPR; -; . DMDM 47116943; -; . REPRODUCTION-2DPAGE IPI00037448; -; . UCD-2DPAGE Q9UBQ7; -; . EPD Q9UBQ7; -; . PaxDb Q9UBQ7; -; . PeptideAtlas Q9UBQ7; -; . PRIDE Q9UBQ7; -; . DNASU 9380; -; . Ensembl ENST00000318158; ENSP00000313432; ENSG00000137106. [Q9UBQ7-1]; . Ensembl ENST00000494290; ENSP00000432021; ENSG00000137106. [Q9UBQ7-2]; . GeneID 9380; -; . KEGG hsa:9380; -; . UCSC uc003zzu.2; human. [Q9UBQ7-1]; . CTD 9380; -; . DisGeNET 9380; -; . GeneCards GRHPR; -; . GeneReviews GRHPR; -; . HGNC HGNC:4570; GRHPR; . HPA HPA022971; -; . MalaCards GRHPR; -; . MIM 260000; phenotype; . MIM 604296; gene; . neXtProt NX_Q9UBQ7; -; . OpenTargets ENSG00000137106; -; . Orphanet 93599; Primary hyperoxaluria type 2; . PharmGKB PA28965; -; . eggNOG KOG0069; Eukaryota; . eggNOG COG1052; LUCA; . GeneTree ENSGT00510000046913; -; . HOGENOM HOG000136702; -; . HOVERGEN HBG051838; -; . InParanoid Q9UBQ7; -; . KO K00049; -; . OMA HRTRNTM; -; . PhylomeDB Q9UBQ7; -; . TreeFam TF324791; -; . Reactome R-HSA-389661; Glyoxylate metabolism and glycine degradation; . SABIO-RK Q9UBQ7; -; . ChiTaRS GRHPR; human; . EvolutionaryTrace Q9UBQ7; -; . GeneWiki GRHPR; -; . GenomeRNAi 9380; -; . PRO PR:Q9UBQ7; -; . Proteomes UP000005640; Chromosome 9; . Bgee ENSG00000137106; -; . CleanEx HS_GRHPR; -; . ExpressionAtlas Q9UBQ7; baseline and differential; . Genevisible Q9UBQ7; HS; . GO GO:0005737; C:cytoplasm; IDA:LIFEdb; . GO GO:0005829; C:cytosol; IEA:Ensembl; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005782; C:peroxisomal matrix; TAS:Reactome; . GO GO:0031406; F:carboxylic acid binding; IEA:Ensembl; . GO GO:0008465; F:glycerate dehydrogenase activity; IDA:UniProtKB; . GO GO:0030267; F:glyoxylate reductase (NADP) activity; IDA:UniProtKB; . GO GO:0016618; F:hydroxypyruvate reductase activity; IDA:UniProtKB; . GO GO:0051287; F:NAD binding; TAS:UniProtKB; . GO GO:0070402; F:NADPH binding; IDA:UniProtKB; . GO GO:0042803; F:protein homodimerization activity; IDA:UniProtKB; . GO GO:0043648; P:dicarboxylic acid metabolic process; IEA:Ensembl; . GO GO:0007588; P:excretion; IMP:UniProtKB; . GO GO:0046487; P:glyoxylate metabolic process; TAS:Reactome; . GO GO:0008152; P:metabolic process; NAS:UniProtKB; . GO GO:0055114; P:oxidation-reduction process; IDA:UniProtKB; . GO GO:0051259; P:protein oligomerization; IDA:UniProtKB; . Gene3D 3.40.50.720; -; 2; . InterPro IPR006139; D-isomer_2_OHA_DH_cat_dom; . InterPro IPR029753; D-isomer_DH_CS; . InterPro IPR006140; D-isomer_DH_NAD-bd; . InterPro IPR016040; NAD(P)-bd_dom; . Pfam PF00389; 2-Hacid_dh; 1; . Pfam PF02826; 2-Hacid_dh_C; 1; . SUPFAM SSF51735; SSF51735; 1; . PROSITE PS00671; D_2_HYDROXYACID_DH_3; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

[Home]